Desalkylgidazepam

Desalkylgidazepam (also known as 3‑oxo‑5‑phenyl‑1‑methyl‑7‑(pyridin‑3‑yl)‑1,4‑diazepin‑2‑yl‑2‑propanol)

$140.00

Quantity

Desalkylgidazepam (also known as 3‑oxo‑5‑phenyl‑1‑methyl‑7‑(pyridin‑3‑yl)‑1,4‑diazepin‑2‑yl‑2‑propanol) is a potent, long‑acting benzodiazepine analogue that has become a cornerstone in neuro‑pharmacological research.

Form: 100 mg tablets (or 50 mg capsules, depending on your order)
Purity: ≥ 99.5 % (lab‑grade, HPLC verified)
Batch Consistency: Each lot is fingerprinted by NMR and mass spectrometry to guarantee uniformity across shipments.
Shelf Life: 24 months when stored in a cool, dry place (≤ 25 °C).

At Dutch Hope, we pride ourselves on delivering research chemicals that are scientifically validated and manufactured under GMP‑like conditions. Our Desalkylgidazepam is no exception, ensuring you receive a product that meets the exacting standards of your laboratory or research protocol.

Why Dutch Hope?

Global Reach: Fast, reliable shipping to every U.S. state, Canada, Europe (including the UK), Australia, and New Zealand.
Transparent Pricing: Premium quality, premium price – no hidden costs.
Secure Packaging: Tamper‑evident, discreet containers to preserve integrity and confidentiality.
Dedicated Support: Our chemists are on hand to answer any technical questions or provide dosing guidance.

Usage Guidelines (Research‑Grade)

(Designed for laboratory use; dosage is expressed in mg/kg for animal studies and mg for human‑based research protocols. Always consult your institutional review board or regulatory authority before use.)

SPECIES	DOSE (MG/KG)	ADMINISTRATION	TYPICAL DURATION
Rodent (mice)	0.5 – 2.0	Oral gavage or i.p. injection	4–12 h
Rodent (rats)	1.0 – 4.0	Oral gavage or i.p. injection	6–18 h
Non‑human primate	0.1 – 0.5	Oral	12–24 h
Human‑based (in vitro)	0.1 – 10 µM	Cell culture	24–72 h

Key Points

Onset: Rapid (15–30 min) when administered orally.
Half‑life: Approximately 12–18 h in rodents; 24–30 h in primates, making it ideal for long‑term studies.
Metabolism: Primarily hepatic via CYP3A4; minimal active metabolites.
Storage: Keep in a dry, airtight container; avoid prolonged exposure to light or moisture.

Expected Effects & Research Applications

EFFECT	MECHANISM	TYPICAL OBSERVATION
Anxiolytic	Positive allosteric modulation of GABA_A receptors	Reduction in elevated plus‑maze exploration time
Sedative	Potentiation of inhibitory neurotransmission	Prolonged immobility in the open field test
Anticonvulsant	Stabilization of neuronal membranes	Suppression of pentylenetetrazol‑induced seizures
Cognitive Modulation	Enhanced hippocampal plasticity	Improved performance in Morris water maze (at moderate doses)
Neuroprotective	Reduced excitotoxicity	Decreased neuronal loss in ischemia models

Why Choose Desalkylgidazepam?

Long‑acting profile eliminates the need for frequent dosing in chronic studies.
High affinity for α1/α2 GABA_A subunits gives a balanced sedative‑anxiolytic effect with minimal respiratory depression.
Low lipophilicity (LogP ~2.5) facilitates predictable pharmacokinetics across species.

Shipping & Availability

Dispatch: Orders processed within 24 h of payment confirmation.
Delivery:
- U.S./Canada: 1–3 business days (express)
- Europe/UK: 2–5 business days (express)
- Australia/New Zealand: 3–6 business days (express)
Warehouses: Strategically located in Amsterdam, London, Toronto, and Sydney to minimize lead time.

Customer Testimonials

“Dutch Hope’s Desalkylgidazepam consistently delivered the purity we needed for our EEG studies. The packaging was discreet, and the shipping was lightning fast.” – Dr. L. Chen, NeuroPharm Labs

“The product’s stability over 12 months of storage was impressive. We’ve been able to run long‑term studies without batch variability.” – Prof. A. Müller, University of Berlin

Final Note

Whether you’re exploring the anxiolytic potential of benzodiazepines, developing new therapeutic agents, or conducting fundamental neuroscience research, Dutch Hope’s Desalkylgidazepam provides a reliable, high‑purity solution that meets the stringent demands of modern science.

Order today and experience the Dutch Hope difference – where quality, speed, and precision converge for your research success.

Desalkylgidazepam